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5-MES-DMT

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Also known as INDOLE, 3-[2-(DIMETHYLAMINO)ETHYL]-5-METHYLTHIO, N,N-DIMETHYL-5-METHYLTHIOTRYPTAMINE

As a sulfur-for-oxygen analogue of 5-MeO-DMT, this compound unexpectedly appears about half as potent rather than stronger, contrary to the potency boost such substitution gives in the phenethylamine series. Related sulfur analogues showed a systematic decline in potency in animal behavioral tests, but their human effects remain to be determined.

Oral

Route dataTiHKAL

ThresholdLightCommonStrongHeavy
15–30 mg—+
030 mg
LightCommonStrongHeavy
Total1–1 hours
Plan when to take 5-MES-DMT — see where onset, peak and comedown land on the clock

Fact-sheets from PsychonautWiki. Harm-reduction reference only — not medical advice.