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Also known as HXE

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Addiction potential
moderately addictive with a high potential for abuse
Tolerance
full tolerance develops with prolonged and repeated use; half after 3 - 7 days; baseline after 1 - 2 weeks
Cross-tolerance
dissociative

Insufflated

Route dataPsychonautWiki

ThresholdLightCommonStrongHeavy
20 mg40–20 mg40–70 mg70–120 mg120 mg+
0150 mg
LightCommonStrongHeavy
Onset10–30 minutes
Come-up20–40 minutes
Peak1.5–4 hours
Offset2–4 hours
Total3–6 hours
After-effects2–7 hours
OnsetCome-upPeakOffset

Oral

Route dataPsychonautWiki

ThresholdLightCommonStrongHeavy
30 mg30–60 mg60–100 mg100–130 mg130 mg+
0162.5 mg
LightCommonStrongHeavy
Onset20–60 minutes
Come-up30–60 minutes
Peak2–4 hours
Offset3–6 hours
Total3–8 hours
After-effects1–12 hours
OnsetCome-upPeakOffset

Sublingual

Route dataPsychonautWiki

ThresholdLightCommonStrongHeavy
30 mg30–60 mg60–100 mg100–130 mg130 mg+
0162.5 mg
LightCommonStrongHeavy
Onset20–60 minutes
Come-up30–60 minutes
Peak2–4 hours
Offset2–6 hours
Total3–6 hours
After-effects1–12 hours
OnsetCome-upPeakOffset
Plan when to take HXE — see where onset, peak and comedown land on the clock

Source: PsychonautWiki — HXE ↗

Fact-sheets from PsychonautWiki. Harm-reduction reference only — not medical advice.