Inhalants

It is never ever safe to ingest inhalants (except alcohols) or directly inhale compressed gases! Short-term moderate inhalation of properly administered medical inhalants (e.g. alkyl nitrites (poppers), or nitrous oxide (when supplemented with vitamin B12 after use to prevent deficiency) can be safe. However, inhalants that are not designed for medical use (e.g. medical gasoline) are considered toxic inhalants, and even a single session of using them can result in sudden death,[1][2] and can cause chronic solvent-induced encephalopathy (CSE), and volatile inhalant withdrawal with frequent use. Unlike other substances, there is no such thing as safe recreational use of volatile solvents without medical use (street inhalants)—their psychoactive effects are inseparable from nerve and organ damage. Additionally, aerosol spray dispensers can cause aerosol burn and hypoxia (lack of oxygen).

Source: PsychonautWiki — Inhalants ↗