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Kanna

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A South African plant containing numerous psychoactive alkaloids, including mesembrine and mesembrenone. The first written account of the substance was in 1662. The pharmacology of these compounds is poorly understood, but they are suspected to be serotonin uptake inhibitors and potentially monoamine releasers. Said to suppress appetite, produce mild euphoria and reduce anxiety.

Insufflated

Route dataTripSit

ThresholdLightCommonStrongHeavy
10–20 mg20–50 mg50–150 mg—+
0150 mg
LightCommonStrongHeavy
After-effects1–8 hours

Oral

Route dataTripSit

ThresholdLightCommonStrongHeavy
250–500 mg500–1000 mg1000–2000 mg—+
02000 mg
LightCommonStrongHeavy
After-effects1–8 hours

Vapourized

Route dataTripSit

ThresholdLightCommonStrongHeavy
30–50 mg50–100 mg100–250 mg—+
0250 mg
LightCommonStrongHeavy
After-effects1–8 hours

Source: TripSit — Kanna ↗

Fact-sheets from PsychonautWiki. Harm-reduction reference only — not medical advice.