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Psilocybin mushrooms

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Also known as Psilocybin, Psilocybin mushrooms, Magic Mushrooms, Shrooms, 4-PO-DMT

Exercise caution when consuming wild psilocybin mushrooms. If consuming mushrooms harvested in nature, it is important to understand the risk of mistakenly consuming a poisonous (potentially fatal) look-alike variety. Please see this section for more information.

Addiction potential
low abuse potential, no physical dependence potential
Toxicity
extremely low toxicity relative to dose
Tolerance
full tolerance almost immediately after ingestion; half after 3 days; baseline after 7 days
Cross-tolerance
psychedelic

Oral

Route dataPsychonautWiki

ThresholdLightCommonStrongHeavy
2.5 mg2.5–10 mg10–25 mg25–50 mg50 mg+
062.5 mg
LightCommonStrongHeavy
Onset20–45 minutes
Come-up1–1.5 hours
Peak2–2.5 hours
Offset2.5–3.5 hours
Total6–8 hours
After-effects4–24 hours
OnsetCome-upPeakOffset

Unsafe interactions

Caution / uncertain

Plan when to take Psilocybin mushrooms — see where onset, peak and comedown land on the clock

Source: PsychonautWiki — Psilocybin mushrooms ↗

Fact-sheets from PsychonautWiki. Harm-reduction reference only — not medical advice.