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🔗 MergedComparePsychonautWikiTripSitPharmacology

Collated from PsychonautWiki, TripSit, Pharmacology. Where sources differ (e.g. dosing), Compare shows them side by side.

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Also known as 2-FMAPW

A long-acting stimulant often compared to lisdexamphetamine. Thought to lack some of amphetamine's neurotoxic metabolites. Very functional, and for this reason it is commonly used for studying.TS

Addiction potentialPW
moderately addictive with a high potential for abuse
ToxicityPW
exact toxic dosage is unknown
TolerancePW
full tolerance develops with prolonged and repeated use; half after 3 - 7 days; baseline after 1 - 2 weeks
Cross-tolerancePW
dopamine, stimulant

Insufflated

Route dataPsychonautWiki

ThresholdLightCommonStrongHeavy
5 mg5–15 mg15–30 mg30–50 mg50 mg+
062.5 mg
LightCommonStrongHeavy
Onset20–40 minutes
Come-up10–20 minutes
Peak1–3 hours
Offset1.5–3 hours
Total4–6 hours
After-effects2–4 hours
OnsetCome-upPeakOffset

Oral

Route dataPsychonautWiki

ThresholdLightCommonStrongHeavy
5 mg5–15 mg15–30 mg30–50 mg50 mg+
062.5 mg
LightCommonStrongHeavy
Onset30–60 minutes
Come-up15–40 minutes
Peak2.5–4 hours
Offset2–3 hours
Total7–9 hours
After-effects4–12 hours
OnsetCome-upPeakOffset

Dangerous interactionsPW

🧬 Receptor activityPH

TargetActionAffinitySource
Cytochrome P450 1B1Ki 36000 nMCHEMBL
Cytochrome P450 1A1Ki 88000 nMCHEMBL
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Plan when to take 2-FMA — see where onset, peak and comedown land on the clock

Fact-sheets from PsychonautWiki. Harm-reduction reference only — not medical advice.