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25B-NBOH

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Collated from PsychonautWiki, TripSit, Pharmacology. Where sources differ (e.g. dosing), Compare shows them side by side.

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PsychedelicSubstituted phenethylaminesResearch-chemicalTentativePW

Also known as 25B-NBOH, nboh-2cb, 2cb-nbohPW

25B-NBOH may have the potential to cause serious injury and death. While no deaths have been reported, it is likely that this compound shares a similar toxicity profile with 25B-NBOMe (which has been linked to multiple deaths).[1] It is strongly discouraged to take higher doses of this substance or to insufflate (snort) it. Please see this section for more details.PW

Addiction potentialPW
not habit-forming
ToxicityPW
potentially fatal at heavy dosages
TolerancePW
full tolerance almost immediately after ingestion; half after 1 week; baseline after 2 weeks
Cross-tolerancePW
psychedelic

Sublingual

Route dataTripSit

Dose
WeakerStronger
ThresholdLightCommonStrongHeavy
—200–400 µg400–800 µg——+
0800 µg
LightCommonStrongHeavy
Duration
ShorterLonger
Onset20–40 minutes
Total4–10 hours
After-effects1–12 hours
OnsetCome-upPeakOffset

Dangerous interactionsPW

Lithium

Unsafe interactionsPW

Tramadol

Caution / uncertainPW

CannabisStimulants

🧬 Receptor activityPH

TargetActionAffinitySource
Plasma kallikrein—Ki 100 nMCHEMBL
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Plan when to take 25B-NBOH — see where onset, peak and comedown land on the clock

Fact-sheets from PsychonautWiki. Harm-reduction reference only — not medical advice.