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🔗 MergedComparePsychonautWikiTripSitPharmacology

Collated from PsychonautWiki, TripSit, Pharmacology. Where sources differ (e.g. dosing), Compare shows them side by side.

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Also known as 3-MeO-PCP, 3-MeOPW

3-MeO-PCP may be more likely to cause mania, delusions, and psychosis than other dissociatives.[1][2][3] It is strongly discouraged to take this substance in high dosages, for multiple days in a row, or in combination with other substances that increase the risk of psychosis. Please see this section for more details.PW

Addiction potentialPW
produces dependence with chronic use and has a high potential for abuse
ToxicityPW
toxic dosage is unknown
TolerancePW
full tolerance with prolonged and repeated use; half after 3 - 7 days; baseline after 1 - 2 weeks
Cross-tolerancePW
dissociative

Insufflated

Route dataPsychonautWiki

ThresholdLightCommonStrongHeavy
1 mg2–5 mg5–10 mg10–15 mg—+
015 mg
LightCommonStrongHeavy
Onset5–30 minutes
Come-up45–90 minutes
Peak1.5–2 hours
Offset45–60 minutes
Total3–5 hours
After-effects4–48 hours
OnsetCome-upPeakOffset

Oral

Route dataPsychonautWiki

ThresholdLightCommonStrongHeavy
2 mg4–8 mg8–15 mg15–25 mg25 mg+
031.25 mg
LightCommonStrongHeavy
Onset30–90 minutes
Come-up45–120 minutes
Peak2–3 hours
Offset1–2 hours
Total4–8 hours
After-effects4–48 hours
OnsetCome-upPeakOffset

Smoked

Route dataPsychonautWiki

ThresholdLightCommonStrongHeavy
2 mg5–10 mg10–20 mg20–25 mg25 mg+
031.25 mg
LightCommonStrongHeavy
Total45–120 minutes

Dangerous interactionsPW

🧬 Receptor activityPH

TargetActionAffinitySource
Diacylglycerol O-acyltransferase 1Ki 1.34 nMCHEMBL
UncheckedKi 1.34 nMCHEMBL
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Plan when to take 3-MeO-PCP — see where onset, peak and comedown land on the clock

Fact-sheets from PsychonautWiki. Harm-reduction reference only — not medical advice.