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4-HO-MET

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Class
Dose
Duration

4 sources

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🔗 MergedComparePsychonautWikiTripSitPharmacologyTiHKAL

Collated from PsychonautWiki, TripSit, Pharmacology, TiHKAL. Where sources differ (e.g. dosing), Compare shows them side by side.

Sections
PsychedelicSubstituted tryptaminesResearch-chemicalCommonPW

Also known as 4-HO-MET, Metocin, Methylcybin, Colour, homet, ethocin, 4-INDOLOL, 3-[2-(ETHYLMETHYLAMINO)ETHYL], N-ETHYL-4-HYDROXY-N-METHYLTRYPTAMINE, 3-[2-(ETHYLMETHYLAMINO)ETHYL]-4-INDOLOLPW

A lesser known psychedelic tryptamine. Functional analogue of Psilocin. Very poorly soluble in water and alcohol.TS

Addiction potentialPW
not habit-forming
ToxicityPW
toxic dose is unknown
TolerancePW
full tolerance almost immediately after ingestion; half after 3 days; baseline after 7 days
Cross-tolerancePW
psychedelic

Oral

Route dataPsychonautWiki

Dose
WeakerStronger
ThresholdLightCommonStrongHeavy
5 mg5–15 mg15–25 mg25–45 mg45 mg+
056.25 mg
LightCommonStrongHeavy
Duration
ShorterLonger
Onset15–40 minutes
Come-up30–60 minutes
Peak2–3 hours
Offset1–1.5 hours
Total4–6 hours
After-effects2–12 hours
OnsetCome-upPeakOffset

Smoked

Route dataPsychonautWiki

Dose
WeakerStronger
ThresholdLightCommonStrongHeavy
5 mg10–25 mg25–35 mg35–60 mg60 mg+
075 mg
LightCommonStrongHeavy
Duration
ShorterLonger
Onset15–120 seconds
Total25–45 minutes
OnsetCome-upPeakOffset

Intravenous

Route dataTripSit

Dose
WeakerStronger
ThresholdLightCommonStrongHeavy
——10–15 mg——+
015 mg
LightCommonStrongHeavy
Duration
ShorterLonger
Total3–7 hours
After-effects2–8 hours

Dangerous interactionsPW

Lithium

Unsafe interactionsPW

Tramadol

Caution / uncertainPW

CannabisStimulants

🧬 Receptor activityPH

TargetActionAffinitySource
Vasopressin V1a receptor—Ki 0.032 nMCHEMBL
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Plan when to take 4-HO-MET — see where onset, peak and comedown land on the clock

Fact-sheets from PsychonautWiki. Harm-reduction reference only — not medical advice.