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Adrafinil

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3 sources

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Collated from PsychonautWiki, TripSit, Pharmacology. Where sources differ (e.g. dosing), Compare shows them side by side.

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StimulantNootropicEugeroicBenzhydrylResearch-chemicalHabit-formingPW

Also known as Adrafinil, OlmifonPW

A prodrug to modafinil, this compound is often used to increase wakefulness and alertness. Due to hepatic metabolism it has a slower onset than modafinil and may cause liver damage in excess. Some users have reported acne as an adverse effect. Unregulated in the US.TS

Addiction potentialPW
not addictive with a low potential for abuse
TolerancePW
full tolerance develops with prolonged and repeated use; half after 3 - 7 days; baseline after 1 - 2 weeks
Cross-tolerancePW
benzhydryl, nootropic|nootropics

Oral

Route dataPsychonautWiki

Dose
WeakerStronger
ThresholdLightCommonStrongHeavy
100 mg150–250 mg250–400 mg400–600 mg600 mg+
0750 mg
LightCommonStrongHeavy
Duration
ShorterLonger
Onset1–2 hours
Come-up45–60 minutes
Peak4.5–6 hours
Offset1–3 hours
Total6–12 hours
After-effects2–6 hours
OnsetCome-upPeakOffset

PharmacodynamicsPH

Adrafinil is a prodrug; it is primarily metabolized in vivo to modafinil, resulting in nearly identical pharmacological effects. Unlike modafinil, the active metabolite must accumulate before the drug is able to act. Oral adrafinil without food usually begins to act within 45 minutes to 1 hour.

Plan when to take Adrafinil — see where onset, peak and comedown land on the clock

Fact-sheets from PsychonautWiki. Harm-reduction reference only — not medical advice.