Amobarbital
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| TripSit | Pharmacology | ||
|---|---|---|---|
| Classification | |||
| Class / category | — | ||
| Safety | |||
| Dose · Oral | |||
| Common | 50–75 mg | — | |
| Strong | 75–150 mg | — | |
| Duration | |||
| Onset | 10–30 minutes | — | |
| Total | 5–9 hours | — | |
| After-effects | 2–12 hours | — | |
| Pharmacology | |||
| Half-life | — | Following bolus iv administration, plasma concentrations of amobarbital decline in a biphasic manner with a half-life of about 40 minutes for the first phase and 20-25 hours for the second phase, although the second phase half-life has ranged from 14-42 hours in individual patients. The half-life of amobarbital was investigated in 36 unrelated subjects; half-life (23.8 hr) appeared to be normally distributed. Following im injection of amylobarbitone sodium 200 mg to mildly hypertensive women in labor 0.7 to 3.5 hr before delivery, the plasma-half-life of amylobarbitone was 2.5 times as long in the neonates as in the mothers. /Amobarbital sodium/ | |
TripSit summary
A sedative and hypnotic barbiturate first discovered in 1923. Formerly widely used recreationally and medically, barbiturates have declined in popularity with the appearance of benzodiazepines and other drugs with less serious consequences in overdose.
Fact-sheets from PsychonautWiki. Harm-reduction reference only — not medical advice.