Dexmethylphenidate
4 sources
How the databases line up — = agree, ≈ partial, ≠ differ. In lists, shared items appear in every source and unique ones in only one (matched case-insensitively).
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| TripSit | Pharmacology | DrugCentral | DailyMed | ||
|---|---|---|---|---|---|
| Classification | |||||
| Class / category | — | — | — | ||
| Also known as | dexmethylphenidatedextromethylphenidate | — | — | — | |
| Safety | |||||
| Dose · Oral | |||||
| Light | 10–20 mg | — | — | — | |
| Common | 20–30 mg | — | — | — | |
| Strong | 30–40 mg | — | — | — | |
| Heavy | 40 mg+ | — | — | — | |
| Duration | |||||
| Onset | 45–90 minutes | — | — | — | |
| Total | 9–12 hours | — | — | — | |
| After-effects | 1–12 hours | — | — | — | |
| Pharmacology | |||||
| Receptor activity | — | Sodium-dependent dopamine transporterNorepinephrine transporterUnchecked | SLC6A3SLC6A2Drd1 | — | ≠ |
| Half-life | — | The mean terminal half life is approximately 2.2 hours. However other studies have shown 3.8-3.9 hours, or 5.96 hours after intravenous administration and 5.69 hours following an oral dose. | — | — | |
| Protein binding | — | 12-15% of dexmethylphenidate is protein bound. However, other studies have observed 15.2±5.2% protein binding in children and 16.2±1.1% in adults. | — | — | |
TripSit summary
The psychoactive isomer of methylphenidate, mostly used to treat ADHD. Twice as potent as methylphenidate, and is said to have cleaner psychostimulant effects with fewer side effects.
Fact-sheets from PsychonautWiki. Harm-reduction reference only — not medical advice.