Dextropropoxyphene
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How the databases line up — = agree, ≈ partial, ≠ differ. In lists, shared items appear in every source and unique ones in only one (matched case-insensitively).
| PsychonautWiki | TripSit | Pharmacology | DrugCentral | ||
|---|---|---|---|---|---|
| Classification | |||||
| Class / category | — | — | ≈ | ||
| Also known as | DextropropoxyphenePropoxypheneDarvon | darvocetco-proxamolcapadexdi-gesic | — | — | ≠ |
| Safety | |||||
| Addiction potential | moderately addictive with a high potential for abuse | — | — | — | |
| Toxicity | high toxicitypotentially lethal when mixed with depressants like alcohol or benzodiazepinesknown to cause potentially fatal heart arrhythmias | — | — | — | |
| Dangerous interactions | — | — | — | ||
| Dose · Oral | |||||
| Threshold | 15 mg | — | — | — | |
| Light | 30–65 mg | 30–65 mg | — | — | = |
| Common | 65–100 mg | 65–100 mg | — | — | = |
| Strong | 100–200 mg | 100–200 mg | — | — | = |
| Heavy | 200 mg+ | — | — | — | |
| Duration | |||||
| Onset | 20–30 minutes | 20–30 minutes | — | — | = |
| Total | — | 1–3 hours | — | — | |
| After-effects | 1–6 hours | 1–6 hours | — | — | = |
| Pharmacology | |||||
| Receptor activity | — | — | — | OPRM1GRIN3ASCN5A | |
| Half-life | — | — | 6-12 hours Propoxyphene has an elimination half-life of 6-12 hours. The half life of elimination of the parent compound is 6 to 12 hours. The half life of elimination of norpropoxyphene is 30 to 36 hours. ... Norpropoxyphene has a longer plasma half-life in the dog than propoxyphene. /Propoxyphene hydrochloride/ In geriatric patients 70-78 years of age, elimination half-lives of propoxyphene and norpropoxyphene reportedly were 13-35 and 22-41 hours, respectively. | — | |
Dose at a glance
Each database's primary-route ladder on one shared scale — see where ranges line up or shift.
Duration at a glance
Total duration on one shared scale.
PsychonautWiki summary
Fatal overdose may occur when opiates are combined with other depressants such as benzodiazepines, barbiturates, gabapentinoids, thienodiazepines, alcohol or other GABAergic substances.[1] It is strongly discouraged to combine these substances, particularly in common to heavy doses.
TripSit summary
An opioid analgesic that is an optical isomer of levopropoxyphene. Used to treat mild pain and often used for its antitussive properties. It has been taken off the market in Europe and US due to concerns of health issues relating to the Kidney, Liver, Heart and Respiratory Disorders. Just a bit stronger than Tramadol.
Fact-sheets from PsychonautWiki. Harm-reduction reference only — not medical advice.