DOB
Discover related
4 sources
Collated from PsychonautWiki, TripSit, Pharmacology, PiHKAL. Where sources differ (e.g. dosing), Compare shows them side by side.
Also known as DOB, Brolamfetamine, Bromo-DMA, 2,5-DIMETHOXY-4-BROMOAMPHETAMINEPW
DOB is a relatively uncommon synthetic psychedelic. It is best known for its very low doses and long duration. Historically it has rarely been taken deliberately, but in place of LSD, however it has recently found its own place in the research chemical scene.TS
Addiction potentialPW
not habit-forming
ToxicityPW
toxic dose is unknown
TolerancePW
full tolerance almost immediately after ingestion; half after 4-7 days; baseline after 7-10 days
Cross-tolerancePW
psychedelic
Oral
Route dataPsychonautWiki
| Threshold | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| 0.2 mg | 0.2–0.75 mg | 0.75–1.75 mg | 1.75–3 mg | 3 mg+ |
03.75 mg
LightCommonStrongHeavy
| Onset | 30–90 minutes |
|---|---|
| Come-up | 2–4 hours |
| Peak | 6–10 hours |
| Offset | 4–8 hours |
| Total | 14–24 hours |
| After-effects | 4–16 hours |
OnsetCome-upPeakOffset
Dangerous interactionsPW
Unsafe interactionsPW
Caution / uncertainPW
🧬 Receptor activityPH
| Target | Action | Affinity | Source | |
|---|---|---|---|---|
| 5-hydroxytryptamine receptor 2A | — | Ki 0.2 nM | CHEMBL | Target5-hydroxytryptamine receptor 2A Action— AffinityKi 0.2 nM SourceCHEMBL |
| Serotonin 2 (5-HT2) receptor | — | Ki 0.39 nM | CHEMBL | TargetSerotonin 2 (5-HT2) receptor Action— AffinityKi 0.39 nM SourceCHEMBL |
| Serotonin receptor 2a and 2c (5HT2A and 5HT2C) | — | Ki 0.4 nM | CHEMBL | TargetSerotonin receptor 2a and 2c (5HT2A and 5HT2C) Action— AffinityKi 0.4 nM SourceCHEMBL |
| 5-hydroxytryptamine receptor 2C | — | Ki 50 nM | CHEMBL | Target5-hydroxytryptamine receptor 2C Action— AffinityKi 50 nM SourceCHEMBL |
| Serotonin 1 (5-HT1) receptor | — | Ki 4200 nM | CHEMBL | TargetSerotonin 1 (5-HT1) receptor Action— AffinityKi 4200 nM SourceCHEMBL |
| 5-hydroxytryptamine receptor 1A | — | Ki 6100 nM | CHEMBL | Target5-hydroxytryptamine receptor 1A Action— AffinityKi 6100 nM SourceCHEMBL |
Plan when to take DOB — see where onset, peak and comedown land on the clock
Plan a dose of DOB
Loading the fact-sheet…
Logging a dose needs somewhere to keep it. Start a free session — no signup; it and everything in it expire in 7 days.
External links
Fact-sheets from PsychonautWiki. Harm-reduction reference only — not medical advice.