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Sections

Also known as DOC

Addiction potential
not habit-forming
Toxicity
toxic dose is unknown
Tolerance
full tolerance almost immediately after ingestion; half after 3 days; baseline after 7 days
Cross-tolerance
psychedelic

Insufflated

Route dataPsychonautWiki

ThresholdLightCommonStrongHeavy
0.25 mg0.25–1 mg1–2 mg2–3.5 mg3.5 mg+
04.375 mg
LightCommonStrongHeavy
Onset1–5 minutes
Come-up10–30 minutes
Peak2–6 hours
Offset2–8 hours
After-effects2–24 hours
OnsetCome-upPeakOffset

Oral

Route dataPsychonautWiki

ThresholdLightCommonStrongHeavy
0.5 mg1–2 mg2–4 mg4–6 mg6 mg+
07.5 mg
LightCommonStrongHeavy
Onset1–2 hours
Come-up2–3 hours
Peak6–12 hours
Offset2–8 hours
Total12–24 hours
After-effects6–24 hours
OnsetCome-upPeakOffset

Dangerous interactions

Unsafe interactions

Caution / uncertain

Plan when to take DOC — see where onset, peak and comedown land on the clock

Source: PsychonautWiki — DOC ↗

Fact-sheets from PsychonautWiki. Harm-reduction reference only — not medical advice.