DOET
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3 sources
Collated from TripSit, Pharmacology, PiHKAL. Where sources differ (e.g. dosing), Compare shows them side by side.
Also known as doe, HECATE, 2,5-DIMETHOXY-4-ETHYLAMPHETAMINETS
A potent and long acting psychedelic stimulant and substituted amphetamine, similar in effects to other DOx compounds. First synthesised by Alexander Shulgin.TS
Oral
Route dataTripSit
| Threshold | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| 1 mg | 2–4 mg | 4–6 mg | 6–10 mg | —+ |
010 mg
LightCommonStrongHeavy
| Onset | 1–3 hours |
|---|---|
| Total | 12–30 hours |
| After-effects | 12–72 hours |
OnsetCome-upPeakOffset
🧬 Receptor activityPH
| Target | Action | Affinity | Source | |
|---|---|---|---|---|
| 5-hydroxytryptamine receptor 2A | — | Ki 100 nM | CHEMBL | Target5-hydroxytryptamine receptor 2A Action— AffinityKi 100 nM SourceCHEMBL |
| Serotonin 2 (5-HT2) receptor | — | Ki 100 nM | CHEMBL | TargetSerotonin 2 (5-HT2) receptor Action— AffinityKi 100 nM SourceCHEMBL |
| 5-hydroxytryptamine receptor 2C | — | Ki 101 nM | CHEMBL | Target5-hydroxytryptamine receptor 2C Action— AffinityKi 101 nM SourceCHEMBL |
| Serotonin 1 (5-HT1) receptor | — | Ki 4570 nM | CHEMBL | TargetSerotonin 1 (5-HT1) receptor Action— AffinityKi 4570 nM SourceCHEMBL |
Plan when to take DOET — see where onset, peak and comedown land on the clock
Plan a dose of DOET
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