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Escitalopram

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🔗 MergedCompareTripSitPharmacologyDrugCentralDailyMed

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TripSitPharmacologyDrugCentralDailyMed
Classification
Class / category
Also known as
lexaprocipralex
Safety
Duration
Pharmacology
Receptor activity
Sodium-dependent serotonin transporter
SLC6A4HTR2CADRA1AHRH1CHRM1Slc6a3SLC6A2NET
Half-lifeThe elimination half-life of escitalopram is 27-32 hours, though this is increased by approximately 50% in the elderly and doubled in patients with reduced hepatic function. The elimination half-life of escitalopram's primary metabolite, S-desmethylcitalopram, is approximately 54 hours at steady state. Biotransformation of escitalopram is mainly hepatic, with a mean terminal half-life of about 27-32 hours.
Protein bindingEscitalopram exhibits relatively low protein binding at approximately 55-56%.

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