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Also known as Etizolam, Etilaam, Etizest, Depas

Fatal overdose may occur when thienodiazepines are combined with other depressants such as opiates, benzodiazepines, barbiturates, gabapentinoids, alcohol or other GABAergic substances.[1] It is strongly discouraged to combine these substances, particularly in common to heavy doses.

Addiction potential
highly addictive with a high potential for abuse
Toxicity
low toxicity; potentially lethal when mixed with depressants like alcohol or opioids
Tolerance
full tolerance within a couple of days of continuous use; baseline after 7 - 14 days
Cross-tolerance
benzodiazepine, thienodiazepine

Oral

Route dataPsychonautWiki

ThresholdLightCommonStrongHeavy
0.2 mg0.5–1 mg1–2 mg2–5 mg5 mg+
06.25 mg
LightCommonStrongHeavy
Onset15–30 minutes
Come-up30–60 minutes
Peak2–3 hours
Offset1.5–2.5 hours
Total5–7 hours
After-effects6–24 hours
OnsetCome-upPeakOffset
Plan when to take Etizolam — see where onset, peak and comedown land on the clock

Source: PsychonautWiki — Etizolam ↗

Fact-sheets from PsychonautWiki. Harm-reduction reference only — not medical advice.