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Also known as GHB, G, Xyrem, Sodium oxybate

Fatal overdose may occur when GABAergic substances are combined with other depressants such as opiates, benzodiazepines, barbiturates, gabapentinoids, thienodiazepines or alcohol.[1] It is strongly discouraged to combine these substances, particularly in common to heavy doses.

Addiction potential
moderately to highly physically and moderately psychologically addictive
Toxicity
considered to be a safe and non-toxic substance when used responsibly or medically; Doses above 10 grams are associated with a risk of death
Tolerance
full tolerance within several days of continuous use; baseline after 7 - 14 days

Oral

Route dataPsychonautWiki

ThresholdLightCommonStrongHeavy
0.5 g0.5–1 g1–2.5 g2.5–4 g4 g+
05 g
LightCommonStrongHeavy
Onset5–30 minutes
Come-up10–20 minutes
Peak45–90 minutes
Offset15–30 minutes
Total1.5–2.5 hours
After-effects2–4 hours
OnsetCome-upPeakOffset
Plan when to take GHB — see where onset, peak and comedown land on the clock

Source: PsychonautWiki — GHB ↗

Fact-sheets from PsychonautWiki. Harm-reduction reference only — not medical advice.