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Lisdexamfetamine

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Classification
Class / category
Also known as
LisdexamfetamineVyvanseElvanse
Safety
Dangerous interactions
Unsafe interactions
Dose · Oral
Threshold10 mg
Light20–30 mg
Common30–60 mg
Strong60–90 mg
Heavy90 mg+
Duration
Onset60–90 minutes
Total10–14 hours
After-effects2–6 hours
Pharmacology
Receptor activity
SLC6A3SLC6A2SLC18A2
Half-lifePlasma concentrations of unconverted lisdexamfetamine are low and transient, generally becoming non-quantifiable by 8 hours after administration. The plasma elimination half-life of lisdexamfetamine typically averaged less than one hour in volunteers ages six years and older. The plasma elimination half-life of dextroamphetamine was approximately 8.6 to 9.5 hours in pediatric patients six to 12 years and 10 to 11.3 hours in healthy adults. The plasma elimination half-life of lisdexamfetamine typically averaged less than one hour in studies of lisdexamfetamine dimesylate in volunteers.

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