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Also known as Mescaline, Peyote, San Pedro, Cactus, Buttons

Addiction potential
not habit-forming
Toxicity
toxic dose is unknown
Tolerance
full tolerance almost immediately after ingestion; half after 3 days; baseline after 7 days
Cross-tolerance
psychedelic

Oral

Route dataPsychonautWiki

ThresholdLightCommonStrongHeavy
50 mg50–200 mg200–400 mg400–800 mg800 mg+
01000 mg
LightCommonStrongHeavy
Onset45–90 minutes
Come-up60–120 minutes
Peak4–6 hours
Offset2–3 hours
Total8–14 hours
After-effects6–36 hours
OnsetCome-upPeakOffset

Dangerous interactions

Unsafe interactions

Plan when to take Mescaline — see where onset, peak and comedown land on the clock

Source: PsychonautWiki — Mescaline ↗

Fact-sheets from PsychonautWiki. Harm-reduction reference only — not medical advice.