🧬 Receptor activity
| Target | Action | Affinity | Source | |
|---|---|---|---|---|
| 5-hydroxytryptamine receptor 7 | — | Ki 0.9333 nM | CHEMBL | Target5-hydroxytryptamine receptor 7 Action— AffinityKi 0.9333 nM SourceCHEMBL |
| Serotonin 1 (5-HT1) receptor | — | Ki 2 nM | CHEMBL | TargetSerotonin 1 (5-HT1) receptor Action— AffinityKi 2 nM SourceCHEMBL |
| 5-hydroxytryptamine receptor 1A | — | Ki 3.2 nM | CHEMBL | Target5-hydroxytryptamine receptor 1A Action— AffinityKi 3.2 nM SourceCHEMBL |
| 5-hydroxytryptamine receptor 1B | — | Ki 3.5 nM | CHEMBL | Target5-hydroxytryptamine receptor 1B Action— AffinityKi 3.5 nM SourceCHEMBL |
| 5-hydroxytryptamine receptor 1D | — | Ki 4.1 nM | CHEMBL | Target5-hydroxytryptamine receptor 1D Action— AffinityKi 4.1 nM SourceCHEMBL |
| Serotonin 2 (5-HT2) receptor | — | Ki 4.8 nM | CHEMBL | TargetSerotonin 2 (5-HT2) receptor Action— AffinityKi 4.8 nM SourceCHEMBL |
| 5-hydroxytryptamine receptor 2A | — | Ki 4.8 nM | CHEMBL | Target5-hydroxytryptamine receptor 2A Action— AffinityKi 4.8 nM SourceCHEMBL |
| 5-hydroxytryptamine receptor 4 | — | Ki 26.92 nM | CHEMBL | Target5-hydroxytryptamine receptor 4 Action— AffinityKi 26.92 nM SourceCHEMBL |
| 5-hydroxytryptamine receptor 2C | — | Ki 45 nM | CHEMBL | Target5-hydroxytryptamine receptor 2C Action— AffinityKi 45 nM SourceCHEMBL |
| Unchecked | — | Ki 45.8 nM | CHEMBL | TargetUnchecked Action— AffinityKi 45.8 nM SourceCHEMBL |
| 5-hydroxytryptamine receptor 6 | — | Ki 50 nM | CHEMBL | Target5-hydroxytryptamine receptor 6 Action— AffinityKi 50 nM SourceCHEMBL |
Pharmacokinetics
Metabolism
5-methoxytryptamine has known human metabolites that include serotonin.
External links
PubChem 1833 ↗CAS 608-07-1 ↗KEGG C05659 ↗ChEBI CHEBI:2089 ↗ChEMBL CHEMBL8165 ↗NIH ↗NIH ↗ChemSpider ↗ChemSpider ↗ChEBI/ChEMBL ↗ChEBI/ChEMBL ↗Guide to Pharmacology ↗NIH ↗NIH ↗ChEBI/ChEMBL ↗NIH ↗NIH ↗NIH ↗NIH ↗NIH ↗CAS 66-83-1 ↗CAS 68160-56-5 ↗CAS 96236-05-4 ↗PsychonautWiki ↗Erowid ↗Experience reports (PiHKAL) ↗Experience reports (TiHKAL) ↗
Fact-sheets from PsychonautWiki. Harm-reduction reference only — not medical advice.