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Pemoline

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🔗 MergedCompareTripSitPharmacologyDrugCentral

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TripSitPharmacologyDrugCentral
Classification
Class / category
Safety
Dose · Oral
Light10–20 mg
Common20–40 mg
Strong40–80 mg
Duration
Onset15–30 minutes
Total4–6 hours
After-effects1–6 hours
Pharmacology
Receptor activity
Sodium-dependent dopamine transporter
SLC6A3
Half-lifeThe serum half-life of pemoline is approximately 12 hours. Following a single oral dose in healthy adults, the plasma or serum half-life of pemoline has ranged from about 9-14 hr. Following a single oral dose in children, the plasma elimination half-life exhibits considerable interindividual variation, ranging from about 2-12 hr (mean: 8.6 hr). Preliminary evidence suggests that the drug may exhibit nonlinar kinetics in children following multiple dosing, with the elimination half-life increasing substantially. ...
Protein bindingApproximately 50% (bound to plasma proteins).

TripSit summary

A stimulant of the 4-oxazolidinone class. Was used as a medication for ADHD and Narcolepsy, yet was pulled from most markets due to liver failures among children.

Fact-sheets from PsychonautWiki. Harm-reduction reference only — not medical advice.