Collated from TripSit, Pharmacology. Where sources differ (e.g. dosing), Compare shows them side by side.
A sigma-1 receptor agonist derived structurally from PCP. It has cognitive enhancing effects as well as antidepressant effects, and shows promise in treating many nervous system diseases such as ALS and parkinsons.TS
🧬 Receptor activityPH
| Target | Action | Affinity | Source | |
|---|---|---|---|---|
| Sigma non-opioid intracellular receptor 1 | — | Ki 58.7 nM | CHEMBL | TargetSigma non-opioid intracellular receptor 1 Action— AffinityKi 58.7 nM SourceCHEMBL |
| Kappa-type opioid receptor | — | Ki 4000 nM | CHEMBL | TargetKappa-type opioid receptor Action— AffinityKi 4000 nM SourceCHEMBL |
| Delta-type opioid receptor | — | Ki 4000 nM | CHEMBL | TargetDelta-type opioid receptor Action— AffinityKi 4000 nM SourceCHEMBL |
Plan when to take PRE-084 — see where onset, peak and comedown land on the clock
Plan a dose of PRE-084
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Fact-sheets from PsychonautWiki. Harm-reduction reference only — not medical advice.