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🔗 MergedCompareTripSitPharmacology

Collated from TripSit, Pharmacology. Where sources differ (e.g. dosing), Compare shows them side by side.

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A stimulant and dopamine reuptake inhibitor developed in the 1970s, it is frequently used in scientific research but has seen little usage outside of the lab. Similar effects to cocaine, though much longer and without any local anaesthetic action. Probably hard on the nose.TS

Oral

Route dataTripSit

ThresholdLightCommonStrongHeavy
15–20 mg20–30 mg30–60 mg—+
060 mg
LightCommonStrongHeavy
Onset10 minutes
Total45–70 minutes
After-effects1–2 hours
OnsetCome-upPeakOffset

🧬 Receptor activityPH

TargetActionAffinitySource
Sodium-dependent dopamine transporterKi 33.11 nMCHEMBL
Norepinephrine transporterKi 920 nMCHEMBL
Sodium-dependent serotonin transporterKi 1900 nMCHEMBL
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Plan when to take Troparil — see where onset, peak and comedown land on the clock

Fact-sheets from PsychonautWiki. Harm-reduction reference only — not medical advice.