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3C-E

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Class
Dose
Duration

4 sources

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🔗 MergedComparePsychonautWikiTripSitPharmacologyPiHKAL

Collated from PsychonautWiki, TripSit, Pharmacology, PiHKAL. Where sources differ (e.g. dosing), Compare shows them side by side.

Sections
PsychedelicSubstituted amphetaminesResearch-chemicalStimulantPW

Also known as 3C-E, 3C-Escaline, 3,5-DIMETHOXY-4-ETHOXYAMPHETAMINEPW

Three-Carbon Analog of Escaline. Substituted Amphetamine.TS

Addiction potentialPW
not habit-forming
ToxicityPW
toxic dose is unknown
TolerancePW
full tolerance almost immediately after ingestion; half after 3 days; baseline after 7 days
Cross-tolerancePW
psychedelic

Insufflated

Route dataPsychonautWiki

Dose
WeakerStronger
ThresholdLightCommonStrongHeavy
15 mg20–35 mg35–60 mg60–70 mg70 mg+
087.5 mg
LightCommonStrongHeavy
Duration
ShorterLonger
Onset5–90 minutes
Peak4–7 hours
Offset2–5 hours
Total5–12 hours
After-effects3–5 hours
OnsetCome-upPeakOffset

Oral

Route dataPsychonautWiki

Dose
WeakerStronger
ThresholdLightCommonStrongHeavy
20 mg30–40 mg40–60 mg60–80 mg80 mg+
0100 mg
LightCommonStrongHeavy
Duration
ShorterLonger
Onset1–2 hours
Peak4–8 hours
Offset3–6 hours
Total10–16 hours
After-effects3–6 hours
OnsetCome-upPeakOffset

Dangerous interactionsPW

Lithium

Unsafe interactionsPW

Tramadol

Caution / uncertainPW

CannabisStimulants
Plan when to take 3C-E — see where onset, peak and comedown land on the clock

Fact-sheets from PsychonautWiki. Harm-reduction reference only — not medical advice.