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6-APDB

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Class
Dose
Duration

3 sources

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🔗 MergedComparePsychonautWikiTripSitPharmacology

Collated from PsychonautWiki, TripSit, Pharmacology. Where sources differ (e.g. dosing), Compare shows them side by side.

Sections
EntactogenStimulantSubstituted amphetaminesSubstituted phenethylaminesSubstituted benzofuransPsychedelicResearch-chemicalEmpathogenHabit-formingPW

Also known as 6-APDB, 4-desoxy-mdaPW

A stimulant and entactogen related to MDMA and an analogue of MDA. Reported as being fairly psychedlic at higher doses. It is a triple monoamine reuptake inhibitor. Potent full agonist of serotonin 2B receptors.TS

Addiction potentialPW
moderately addictive with a high potential for abuse
ToxicityPW
exact toxic dosage is unknown
TolerancePW
full tolerance with prolonged and repeated use; half after 21-30 days; baseline after 2-3 months
Cross-tolerancePW
dopamine, stimulant

Oral

Route dataPsychonautWiki

Dose
WeakerStronger
ThresholdLightCommonStrongHeavy
20 mg30–70 mg70–100 mg100–130 mg130 mg+
0162.5 mg
LightCommonStrongHeavy
Duration
ShorterLonger
Onset30–60 minutes
Come-up30–60 minutes
Peak2–3 hours
Offset2–3 hours
Total6–8 hours
OnsetCome-upPeakOffset

Unsafe interactionsPW

DXMMDMAStimulants

Caution / uncertainPW

AlcoholMXEDissociatives

🧬 Receptor activityPH

TargetActionAffinitySource
Cannabinoid receptor 1—Ki 2511 nMCHEMBL
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Plan when to take 6-APDB — see where onset, peak and comedown land on the clock

Fact-sheets from PsychonautWiki. Harm-reduction reference only — not medical advice.