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Also known as Amphetamine, Speed, Adderall, Pep

Addiction potential
has high abuse potential and can cause psychological dependence with chronic use
Toxicity
exact toxic dosage is unknown
Tolerance
full tolerance develops with prolonged and repeated use; half after 3 - 7 days; baseline after 1 - 2 weeks
Cross-tolerance
dopamine, stimulant

Insufflated

Route dataPsychonautWiki

ThresholdLightCommonStrongHeavy
4 mg6–15 mg15–30 mg30–50 mg50 mg+
062.5 mg
LightCommonStrongHeavy
Onset1–5 minutes
Come-up30–90 minutes
Peak1–2 hours
Offset1.5–3 hours
Total3–6 hours
After-effects2–4 hours
OnsetCome-upPeakOffset

Intravenous

Route dataPsychonautWiki

ThresholdLightCommonStrongHeavy
4 mg6–15 mg15–30 mg30–50 mg50 mg+
062.5 mg
LightCommonStrongHeavy
Onset2–10 seconds
Come-up2–10 seconds
Peak2–4 hours
Offset1–2 hours
Total3–6 hours
OnsetCome-upPeakOffset

Oral

Route dataPsychonautWiki

ThresholdLightCommonStrongHeavy
2.5 mg5–10 mg10–25 mg25–50 mg50 mg+
062.5 mg
LightCommonStrongHeavy
Onset30–45 minutes
Come-up30–135 minutes
Peak2.5–4 hours
Offset2–3 hours
Total6–8 hours
After-effects3–6 hours
OnsetCome-upPeakOffset

Dangerous interactions

Plan when to take Amphetamine — see where onset, peak and comedown land on the clock

Source: PsychonautWiki — Amphetamine ↗

Fact-sheets from PsychonautWiki. Harm-reduction reference only — not medical advice.