APICA
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2 sources
Collated from PsychonautWiki, Pharmacology. Where sources differ (e.g. dosing), Compare shows them side by side.
Also known as APICA, SDB-001, 2NE1PW
Addiction potentialPW
moderately addictive with a high potential for abuse
ToxicityPW
exact toxic dosage is unknown
TolerancePW
full tolerance develops with prolonged and repeated use; half after 3 - 7 days; baseline after 1 - 2 weeks
Cross-tolerancePW
cannabinoids
Smoked
Route dataPsychonautWiki
| Threshold | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| 0.5 mg | 0.5–1.5 mg | 1.5–2 mg | 2–4 mg | 4 mg+ |
05 mg
LightCommonStrongHeavy
| Onset | 0–20 seconds |
|---|---|
| Peak | 10–30 minutes |
| Offset | 5–10 minutes |
| Total | 30–60 minutes |
| After-effects | 15–35 minutes |
OnsetCome-upPeakOffset
🧬 Receptor activityPH
| Target | Action | Affinity | Source | |
|---|---|---|---|---|
| Metabotropic glutamate receptor 2 | — | Ki 30000 nM | CHEMBL | TargetMetabotropic glutamate receptor 2 Action— AffinityKi 30000 nM SourceCHEMBL |
| Metabotropic glutamate receptor 5 | — | Ki 1000000 nM | CHEMBL | TargetMetabotropic glutamate receptor 5 Action— AffinityKi 1000000 nM SourceCHEMBL |
| Metabotropic glutamate receptor 6 | — | Ki 1000000 nM | CHEMBL | TargetMetabotropic glutamate receptor 6 Action— AffinityKi 1000000 nM SourceCHEMBL |
| Metabotropic glutamate receptor 1 | — | Ki 1000000 nM | CHEMBL | TargetMetabotropic glutamate receptor 1 Action— AffinityKi 1000000 nM SourceCHEMBL |
Plan when to take APICA — see where onset, peak and comedown land on the clock
Plan a dose of APICA
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Fact-sheets from PsychonautWiki. Harm-reduction reference only — not medical advice.