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Also known as coffee

Caffeine is a a CNS stimulant, and also the most widely used psychoactive substance in the world. It is legal and unregulated in most parts of the world, and is found in many commonly sold products. It has a good safety profile, though regular heavy use can cause physical dependence and contribute to certain medical conditions.

Oral

Route dataTripSit

ThresholdLightCommonStrongHeavy
10 mg20–75 mg250–400 mg400 mg+
0500 mg
LightCommonStrongHeavy
Onset5–10 minutes
Total1.5–5 hours
After-effects3–4 hours
OnsetCome-upPeakOffset
Plan when to take Caffeine — see where onset, peak and comedown land on the clock

Source: TripSit — Caffeine ↗

Fact-sheets from PsychonautWiki. Harm-reduction reference only — not medical advice.