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Also known as Cannabis, Marijuana, Weed, Pot, Mary Jane, Grass, Herb, Green, Bud, Tree, THC

Addiction potential
moderately habit-forming
Tolerance
full tolerance develops with prolonged and repeated use; half after 1 - 2 weeks; baseline after 2 - 3 weeks
Cross-tolerance
cannabinoids

Oral

Route dataPsychonautWiki

ThresholdLightCommonStrongHeavy
1 mg2.5–5 mg5–10 mg10–25 mg25 mg+
031.25 mg
LightCommonStrongHeavy
Onset20–60 minutes
Come-up30–60 minutes
Peak1–2 hours
Offset4–6 hours
Total4–10 hours
After-effects6–12 hours
OnsetCome-upPeakOffset

Smoked

Route dataPsychonautWiki

ThresholdLightCommonStrongHeavy
0.4 mg0.4–2 mg2–4 mg4–10 mg10 mg+
012.5 mg
LightCommonStrongHeavy
Onset0.1–10 minutes
Come-up5–10 minutes
Peak15–45 minutes
Offset3–4 hours
Total2.5–5 hours
After-effects45–180 minutes
OnsetCome-upPeakOffset

Sublingual

Route dataPsychonautWiki

Onset1–10 minutes
Come-up15–30 minutes
Peak30–60 minutes
Offset4–6 hours
Total3–7 hours
OnsetCome-upPeakOffset

Dangerous interactions

Plan when to take Cannabis — see where onset, peak and comedown land on the clock

Source: PsychonautWiki — Cannabis ↗

Fact-sheets from PsychonautWiki. Harm-reduction reference only — not medical advice.