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Cinolazepam

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Mechanism of action

Cinolazepam binds to central benzodiazepine receptors which interact allosterically with GABA receptors. This potentiates the effects of the inhibitory neurotransmitter GABA, increasing the inhibition of the ascending reticular activating system and blocking the cortical and limbic arousal that occurs following stimulation of the reticular pathways.

Pharmacodynamics

Cinolazepam is a benzodiazepine derivative with anxiolytic, anticonvulsant, sedative and skeletal muscle relaxant activity. It is not approved in Canada or America.

Pharmacokinetics

Half-life

9 hours

Absorption

Bioavailability following oral administration is 90-100%.

Metabolism

Hepatic.
Hepatic.
Half Life: 9 hours

Fact-sheets from PsychonautWiki. Harm-reduction reference only — not medical advice.