Dextromethorphan
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4 sources
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| PsychonautWiki | TripSit | Pharmacology | DrugCentral | ||
|---|---|---|---|---|---|
| Classification | |||||
| Class / category | — | — | ≈ | ||
| Also known as | DXMDMODMDexRobitussinDelsymDexAloneDuract | dxmrobosyruprobotussindexrobitussin | — | — | ≈ |
| Safety | |||||
| Addiction potential | produces dependence with chronic use and has moderate abuse potential | — | — | — | |
| Toxicity | exact toxic dosage is unknown | — | — | — | |
| Dangerous interactions | — | — | ≈ | ||
| Unsafe interactions | — | — | ≈ | ||
| Dose · Oral | |||||
| Threshold | 75 mg | — | — | — | |
| Light | 100–200 mg | 1.5–2.5 mg | — | — | ≠ |
| Common | 200–400 mg | 2.5–7.5 mg | — | — | ≠ |
| Strong | 400–700 mg | 7.5–15 mg | — | — | ≠ |
| Heavy | 700 mg+ | 15 mg+ | — | — | ≠ |
| Duration | |||||
| Onset | 30–120 minutes | 20–60 minutes | — | — | ≠ |
| Total | 8–12 hours | 6–8 hours | — | — | ≠ |
| After-effects | 4–24 hours | 1–12 hours | — | — | ≠ |
| Pharmacology | |||||
| Receptor activity | — | — | Sodium-dependent serotonin transporterSigma non-opioid intracellular receptor 1UncheckedGlutamate NMDA receptorMuscarinic acetylcholine receptor M2 | GRIN2CGRIN3ASIGMAR1CYP2D6Grin1Scn1aSLC6A4SLC22A1TAS2R46 | ≠ |
| Half-life | — | — | Dextromethorphan has a half life of 3-30 hours. The half life of /dextromethorphan/ is approximately 2 to 4 hours in people with normal metabolism. | — | |
| Protein binding | — | — | Dextromethorphan is 60-70% protein bound in serum. | — | |
Dose at a glance
Each database's primary-route ladder on one shared scale — see where ranges line up or shift.
PsychonautWiki oral
TripSit Oral
0875 mg
LightCommonStrongHeavy
Duration at a glance
Total duration on one shared scale.
PsychonautWiki
TripSit
TripSit summary
Commonly found in certain over the counter cough medicines. Has dissociative effects similar to ketamine or MXE, though also shares properties with opioids and alcohol. Make sure DXM is the only active ingredient in the preparation.
Fact-sheets from PsychonautWiki. Harm-reduction reference only — not medical advice.