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Also known as ro8-4650

A triple monoamine reuptake inhibitor developed by Hoffman-LaRoche in the 1970s as an antidepressant but discontinued, probably due to high abuse potential. Has not become popular as a recreational drug at this time. Acts as an SNDRI, mostly inhibits dopamine and noradrenaline.

Oral

Route dataTripSit

ThresholdLightCommonStrongHeavy
12 mg30–40 mg40–60 mg60 mg+
075 mg
LightCommonStrongHeavy
Total4–6 hours
Plan when to take Diclofensine — see where onset, peak and comedown land on the clock

Source: TripSit — Diclofensine ↗

Fact-sheets from PsychonautWiki. Harm-reduction reference only — not medical advice.