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Doxylamine

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🔗 MergedCompareTripSitPharmacologyDrugCentral

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TripSitPharmacologyDrugCentral
Classification
Class / category
Safety
Dose · Oral
Threshold10 mg
Light75–200 mg
Common200–350 mg
Heavy350 mg+
Duration
Onset20–30 minutes
Total6–8 hours
After-effects1–6 hours
Pharmacology
Receptor activity
HRH1
Half-life10 hours The drug has an elimination half-life of about 10 hours in healthy adults.

TripSit summary

A first generation antihistamine and anticholinergic, originally used to treat nausea and itching, and later as a sleep aid. Causes drowsiness, and delirium in overdose. Sometimes used with opioids to combat nausea and potentiate effects.

Fact-sheets from PsychonautWiki. Harm-reduction reference only — not medical advice.