A first generation antihistamine and anticholinergic, originally used to treat nausea and itching, and later as a sleep aid. Causes drowsiness, and delirium in overdose. Sometimes used with opioids to combat nausea and potentiate effects.
Oral
Route dataTripSit
| Threshold | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| 10 mg | 75–200 mg | 200–350 mg | — | 350 mg+ |
0437.5 mg
LightCommonStrongHeavy
| Onset | 20–30 minutes |
|---|---|
| Total | 6–8 hours |
| After-effects | 1–6 hours |
OnsetCome-upPeakOffset
Plan when to take Doxylamine — see where onset, peak and comedown land on the clock
Plan a dose of Doxylamine
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Source: TripSit — Doxylamine ↗
Fact-sheets from PsychonautWiki. Harm-reduction reference only — not medical advice.