Efavirenz
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4 sources
🧬 Receptor activity
| Target | Action | Affinity | Source | |
|---|---|---|---|---|
| Cytochrome P450 3A4 (CYP3A4) | Inhibitor | 4.76 IC50 | DRUGCENTRAL | TargetCytochrome P450 3A4 (CYP3A4) ActionInhibitor Affinity4.76 IC50 SourceDRUGCENTRAL |
| Gag-Pol polyprotein (gag-pol) | Inhibitor | 8.3 IC50 | DRUGCENTRAL | TargetGag-Pol polyprotein (gag-pol) ActionInhibitor Affinity8.3 IC50 SourceDRUGCENTRAL |
| Reverse transcriptase/RNaseH (pol) | Inhibitor | 8.52 Ki | DRUGCENTRAL | TargetReverse transcriptase/RNaseH (pol) ActionInhibitor Affinity8.52 Ki SourceDRUGCENTRAL |
| Nuclear receptor subfamily 1 group I member 2 (NR1I2) | — | — | DRUGCENTRAL | TargetNuclear receptor subfamily 1 group I member 2 (NR1I2) Action— Affinity— SourceDRUGCENTRAL |
| Reverse transcriptase (reverse transcriptas) | — | 8.89 IC50 | DRUGCENTRAL | TargetReverse transcriptase (reverse transcriptas) Action— Affinity8.89 IC50 SourceDRUGCENTRAL |
| Reverse transcriptase protein (reverse transcriptase) | — | 8.07 Ki | DRUGCENTRAL | TargetReverse transcriptase protein (reverse transcriptase) Action— Affinity8.07 Ki SourceDRUGCENTRAL |
External links
PubChem 64139 ↗CAS 154598-52-4 ↗KEGG C08088 ↗ChEBI CHEBI:119486 ↗ChEMBL CHEMBL223228 ↗KEGG D00896 ↗DrugBank DB00625 ↗NIH ↗NIH ↗NIH ↗NIH ↗NIH ↗ChemSpider ↗ChEBI/ChEMBL ↗ChEBI/ChEMBL ↗Guide to Pharmacology ↗NIH ↗NIH ↗NIH ↗NIH ↗NIH ↗NIH ↗DrugBank ↗ChEBI/ChEMBL ↗NIH ↗NIH ↗NIH ↗NIH ↗NIH ↗NIH ↗CAS 154801-74-8 ↗CAS 177530-93-7 ↗PsychonautWiki ↗Erowid ↗Experience reports (PiHKAL) ↗Experience reports (TiHKAL) ↗
Source: DrugCentral — Efavirenz ↗
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