Fentanyl
Discover related
5 sources
🧬 Receptor activity
| Target | Action | Affinity | Source | |
|---|---|---|---|---|
| Mu-type opioid receptor (OPRM1) | Agonist | 9.001 EC50 | DRUGCENTRAL | TargetMu-type opioid receptor (OPRM1) ActionAgonist Affinity9.001 EC50 SourceDRUGCENTRAL |
| Delta-type opioid receptor (OPRD1) | — | 6.17 Ki | DRUGCENTRAL | TargetDelta-type opioid receptor (OPRD1) Action— Affinity6.17 Ki SourceDRUGCENTRAL |
| Histamine H1 receptor (Hrh1) | — | 4.7 IC50 | DRUGCENTRAL | TargetHistamine H1 receptor (Hrh1) Action— Affinity4.7 IC50 SourceDRUGCENTRAL |
| Kappa-type opioid receptor (OPRK1) | — | 6.71 Ki | DRUGCENTRAL | TargetKappa-type opioid receptor (OPRK1) Action— Affinity6.71 Ki SourceDRUGCENTRAL |
| Monoamine oxidase (MAOA) | — | 5.26 Ki | DRUGCENTRAL | TargetMonoamine oxidase (MAOA) Action— Affinity5.26 Ki SourceDRUGCENTRAL |
| Mu-type opioid receptor (Oprm1) | — | 8.82 Ki | DRUGCENTRAL | TargetMu-type opioid receptor (Oprm1) Action— Affinity8.82 Ki SourceDRUGCENTRAL |
| Opioid receptor (Oprd1) | — | 8.67 Ki | DRUGCENTRAL | TargetOpioid receptor (Oprd1) Action— Affinity8.67 Ki SourceDRUGCENTRAL |
| Potassium voltage-gated channel subfamily H member 2 (KCNH2) | — | 5.74 IC50 | DRUGCENTRAL | TargetPotassium voltage-gated channel subfamily H member 2 (KCNH2) Action— Affinity5.74 IC50 SourceDRUGCENTRAL |
| Sigma non-opioid intracellular receptor 1 (SIGMAR1) | — | 6.45 IC50 | DRUGCENTRAL | TargetSigma non-opioid intracellular receptor 1 (SIGMAR1) Action— Affinity6.45 IC50 SourceDRUGCENTRAL |
| Solute carrier family 22 member 1 (SLC22A1) | — | 4.34 IC50 | DRUGCENTRAL | TargetSolute carrier family 22 member 1 (SLC22A1) Action— Affinity4.34 IC50 SourceDRUGCENTRAL |
External links
PubChem 3345 ↗CAS 437-38-7 ↗ChEBI CHEBI:119915 ↗ChEMBL CHEMBL596 ↗KEGG D00320 ↗DrugBank DB00813 ↗ChemSpider ↗ChEBI/ChEMBL ↗ChEBI/ChEMBL ↗Guide to Pharmacology ↗NIH ↗NIH ↗NIH ↗DrugBank ↗ChEBI/ChEMBL ↗NIH ↗NIH ↗NIH ↗NIH ↗NIH ↗NIH ↗NIH ↗NIH ↗NIH ↗NIH ↗NIH ↗NIH ↗NIH ↗NIH ↗CAS 118357-29-2 ↗CAS 1443-54-5 ↗CAS 150399-23-8 ↗CAS 201415-26-1 ↗PsychonautWiki ↗Erowid ↗Experience reports (PiHKAL) ↗Experience reports (TiHKAL) ↗
Source: DrugCentral — Fentanyl ↗
Fact-sheets from PsychonautWiki. Harm-reduction reference only — not medical advice.