Hydrocodone
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5 sources
How the databases line up — = agree, ≈ partial, ≠ differ. In lists, shared items appear in every source and unique ones in only one (matched case-insensitively).
| PsychonautWiki | TripSit | Pharmacology | DrugCentral | DailyMed | ||
|---|---|---|---|---|---|---|
| Classification | ||||||
| Class / category | — | — | — | ≈ | ||
| Also known as | Vicodin (with paracetamol)Zohydro ER (extended-release)Norco | vicodinhydro | — | — | — | ≠ |
| Safety | ||||||
| Addiction potential | moderately addictive | — | — | — | — | |
| Toxicity | potentially fatal at heavy dosages | — | — | — | — | |
| Dangerous interactions | — | — | — | — | ||
| Dose · Oral | ||||||
| Threshold | 3 mg | — | — | — | — | |
| Light | 5–10 mg | 5–10 mg | — | — | — | = |
| Common | 10–25 mg | 10–25 mg | — | — | — | = |
| Strong | 25–40 mg | 25–40 mg | — | — | — | = |
| Heavy | 40 mg+ | — | — | — | — | |
| Duration | ||||||
| Onset | 10–60 minutes | 10–60 minutes | — | — | — | = |
| Total | 4–8 hours | 4–8 hours | — | — | — | = |
| After-effects | — | 1–12 hours | — | — | — | |
| Pharmacology | ||||||
| Receptor activity | — | — | — | OPRK1OPRM1 | — | |
| Half-life | — | — | The half-life of elimination reported for hydrocodone is 7-9 h. The mean terminal half-life (t1/2) was similar for all HYSINGLA ER dose strengths ranging from 7 to 9 hours. Half-life was determined to be 3.8 +/- 0.3 hrs. The elimination half-life of hydrocodone is reportedly about 3.8 hours in healthy adults. | — | — | |
| Protein binding | — | — | Hydrocodone is 36% bound to plasma proteins. | — | — | |
Dose at a glance
Each database's primary-route ladder on one shared scale — see where ranges line up or shift.
Duration at a glance
Total duration on one shared scale.
PsychonautWiki summary
Fatal overdose may occur when opiates are combined with other depressants such as benzodiazepines, barbiturates, gabapentinoids, thienodiazepines, alcohol or other GABAergic substances.[1] It is strongly discouraged to combine these substances, particularly in common to heavy doses.
TripSit summary
A codeine-derived opioid generally unheard of outside the United States. Generally mild in effects, used as an analgesic and cough-supressant. Sometimes used recreationally.
Fact-sheets from PsychonautWiki. Harm-reduction reference only — not medical advice.