Hydrocodone
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Also known as Vicodin (with paracetamol), Zohydro ER (extended-release), Norco
Fatal overdose may occur when opiates are combined with other depressants such as benzodiazepines, barbiturates, gabapentinoids, thienodiazepines, alcohol or other GABAergic substances.[1] It is strongly discouraged to combine these substances, particularly in common to heavy doses.
Addiction potential
moderately addictive
Toxicity
potentially fatal at heavy dosages
Tolerance
full tolerance with prolonged use; half after 3 - 7 days; baseline after 1 - 2 weeks
Cross-tolerance
opioids
Oral
Route dataPsychonautWiki
| Threshold | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| 3 mg | 5–10 mg | 10–25 mg | 25–40 mg | 40 mg+ |
050 mg
LightCommonStrongHeavy
| Onset | 10–60 minutes |
|---|---|
| Total | 4–8 hours |
OnsetCome-upPeakOffset
Dangerous interactions
Caution / uncertain
Plan when to take Hydrocodone — see where onset, peak and comedown land on the clock
Plan a dose of Hydrocodone
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Source: PsychonautWiki — Hydrocodone ↗
Fact-sheets from PsychonautWiki. Harm-reduction reference only — not medical advice.