How the databases line up — = agree, ≈ partial, ≠ differ. In lists, shared items appear in every source and unique ones in only one (matched case-insensitively).
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| TripSit | Pharmacology | DrugCentral | ||
|---|---|---|---|---|
| Classification | ||||
| Class / category | — | — | ||
| Safety | ||||
| Dose · Oral | ||||
| Common | 400–800 mg | — | — | |
| Duration | ||||
| Onset | 1 hours | — | — | |
| Total | 4–6 hours | — | — | |
| Pharmacology | ||||
| Receptor activity | — | Solute carrier family 22 member 20Solute carrier family 22 member 6Prostaglandin G/H synthase 2Prostaglandin G/H synthase 1Fatty acid-binding protein, liverCytochrome P450 2C9Solute carrier organic anion transporter family member 1A1Dihydrofolate reductaseOrganic anion transporter 3Solute carrier organic anion transporter family member 1A4Albumin | ASIC1PTGS1PTGS2SLC5A8AKR1C2AKR1C3ALOX5CYP2C9Dhrs9Fabp1CXCL8PtgdsALBSlc22a20Slc22a6 | ≠ |
| Half-life | — | The serum half-life of ibuprofen is 1.2-2 hours. In patients with a compromised liver function, the half-life can be prolonged to 3.1-3.4 hours. ... After oral admin ... the half-life in plasma is about 2 hr. | — | |
| Protein binding | — | Ibuprofen dosage is more than 99% bound to plasma proteins and site II of purified albumin, binding appears to be saturable and becomes non-linear at concentrations exceeding 20 mcg/ml. | — | |
TripSit summary
A ubiquitously available pain reliever/fever reducer. Ibuprofen is a nonsteroidal anti-inflammatory drug, available in many forms. It is sometimes used to reduce the body-load caused by certain drugs, such as stimulants.
Fact-sheets from PsychonautWiki. Harm-reduction reference only — not medical advice.