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Methaqualone

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Also known as Methaqualone, Quaaludes, Ludes, Mandrax, Sopor, Quack, Vitamin Q, Soaper

Fatal overdose may occur when GABAergic substances are combined with other depressants such as opiates, benzodiazepines, barbiturates, gabapentinoids, thienodiazepines or alcohol.[1] It is strongly discouraged to combine these substances, particularly in common to heavy doses.

Addiction potential
extremely addictive
Toxicity
doses of over 300mg can be dangerous for first time users; safe at appropriate dosages
Tolerance
full tolerance within a couple of days of repeated administration; half after 3 - 7 days; baseline after 1 - 2 weeks
Cross-tolerance
GABA|gabaergic, depressants

Oral

Route dataPsychonautWiki

ThresholdLightCommonStrongHeavy
75 mg150–300 mg300–500 mg500–600 mg—+
0600 mg
LightCommonStrongHeavy
Peak2–4 hours
Offset2–4 hours
Total5–8 hours
After-effects6–8 hours
OnsetCome-upPeakOffset

Smoked

Route dataPsychonautWiki

ThresholdLightCommonStrongHeavy
50 mg50–100 mg100–200 mg200–300 mg—+
0300 mg
LightCommonStrongHeavy
Total1–2 hours

Dangerous interactions

Caution / uncertain

Plan when to take Methaqualone — see where onset, peak and comedown land on the clock

Source: PsychonautWiki — Methaqualone ↗

Fact-sheets from PsychonautWiki. Harm-reduction reference only — not medical advice.