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🔗 MergedComparePsychonautWikiTripSit

Collated from PsychonautWiki, TripSit. Where sources differ (e.g. dosing), Compare shows them side by side.

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Also known as Metizolam, Desmethyletizolam, metizPW

Fatal overdose may occur when thienodiazepines are combined with other depressants such as opiates, benzodiazepines, barbiturates, gabapentinoids, alcohol or other GABAergic substances.[1] It is strongly discouraged to combine these substances, particularly in common to heavy doses.PW

Addiction potentialPW
extremely addictive
ToxicityPW
large therapeutic index and margin of safety
TolerancePW
full tolerance within a couple of days of repeated administration; half after 3 - 7 days; baseline after 1 - 2 weeks
Cross-tolerancePW
thienzodiazepines, benzodiazepines

Oral

Route dataPsychonautWiki

ThresholdLightCommonStrongHeavy
1–2 mg2–4 mg4–6 mg6 mg+
07.5 mg
LightCommonStrongHeavy
Onset30–90 minutes
Total5–8 hours
After-effects10–30 hours
OnsetCome-upPeakOffset
Plan when to take Metizolam — see where onset, peak and comedown land on the clock

Fact-sheets from PsychonautWiki. Harm-reduction reference only — not medical advice.