Metizolam
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Also known as Metizolam, Desmethyletizolam
Fatal overdose may occur when thienodiazepines are combined with other depressants such as opiates, benzodiazepines, barbiturates, gabapentinoids, alcohol or other GABAergic substances.[1] It is strongly discouraged to combine these substances, particularly in common to heavy doses.
Addiction potential
extremely addictive
Toxicity
large therapeutic index and margin of safety
Tolerance
full tolerance within a couple of days of repeated administration; half after 3 - 7 days; baseline after 1 - 2 weeks
Cross-tolerance
thienzodiazepines, benzodiazepines
Oral
Route dataPsychonautWiki
| Threshold | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| — | 1–2 mg | 2–4 mg | 4–6 mg | 6 mg+ |
07.5 mg
LightCommonStrongHeavy
| Onset | 30–90 minutes |
|---|---|
| Total | 5–8 hours |
| After-effects | 10–30 hours |
OnsetCome-upPeakOffset
Plan when to take Metizolam — see where onset, peak and comedown land on the clock
Plan a dose of Metizolam
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Source: PsychonautWiki — Metizolam ↗
Fact-sheets from PsychonautWiki. Harm-reduction reference only — not medical advice.