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A common hypnotic, sedative and anxiolytic benzodiazepine. High doses may cause amnesia and loss of inhibitions. Unusually, it is water soluble, and commonly used as a premedication for sedation as the solubility makes it better for IV use than other benzodiazepines.

Insufflated

Route dataTripSit

ThresholdLightCommonStrongHeavy
3–7 mg7–15 mg15–25 mg—+
025 mg
LightCommonStrongHeavy
Total4–8 hours
After-effects1–12 hours

Intramuscular

Route dataTripSit

ThresholdLightCommonStrongHeavy
3–5 mg5–12 mg12–25 mg—+
025 mg
LightCommonStrongHeavy
Total4–8 hours
After-effects1–12 hours

Intravenous

Route dataTripSit

ThresholdLightCommonStrongHeavy
2.5–5 mg5–10 mg10–20 mg—+
020 mg
LightCommonStrongHeavy
Total4–8 hours
After-effects1–12 hours

Oral

Route dataTripSit

ThresholdLightCommonStrongHeavy
5–10 mg10–15 mg15–30 mg—+
030 mg
LightCommonStrongHeavy
Total4–8 hours
After-effects1–12 hours

Rectal

Route dataTripSit

ThresholdLightCommonStrongHeavy
3–7 mg7–15 mg—+
015 mg
LightCommonStrongHeavy
Total4–8 hours
After-effects1–12 hours
Plan when to take Midazolam — see where onset, peak and comedown land on the clock

Source: TripSit — Midazolam ↗

Fact-sheets from PsychonautWiki. Harm-reduction reference only — not medical advice.