Mirtazapine
Discover related
4 sources
🧬 Receptor activity
| Target | Action | Affinity | Source | |
|---|---|---|---|---|
| 5-hydroxytryptamine receptor 2A (HTR2A) | Antagonist | 7.16 Ki | DRUGCENTRAL | Target5-hydroxytryptamine receptor 2A (HTR2A) ActionAntagonist Affinity7.16 Ki SourceDRUGCENTRAL |
| 5-hydroxytryptamine receptor 2C (HTR2C) | Antagonist | 7.41 Ki | DRUGCENTRAL | Target5-hydroxytryptamine receptor 2C (HTR2C) ActionAntagonist Affinity7.41 Ki SourceDRUGCENTRAL |
| Alpha-2A adrenergic receptor (ADRA2A) | Antagonist | 7.7 Ki | DRUGCENTRAL | TargetAlpha-2A adrenergic receptor (ADRA2A) ActionAntagonist Affinity7.7 Ki SourceDRUGCENTRAL |
| Alpha-2B adrenergic receptor (ADRA2B) | Antagonist | 6.65 IC50 | DRUGCENTRAL | TargetAlpha-2B adrenergic receptor (ADRA2B) ActionAntagonist Affinity6.65 IC50 SourceDRUGCENTRAL |
| Alpha-2C adrenergic receptor (ADRA2C) | Antagonist | 7.74 Ki | DRUGCENTRAL | TargetAlpha-2C adrenergic receptor (ADRA2C) ActionAntagonist Affinity7.74 Ki SourceDRUGCENTRAL |
| 5-hydroxytryptamine receptor 1A (HTR1A) | — | 5.3 Kd | DRUGCENTRAL | Target5-hydroxytryptamine receptor 1A (HTR1A) Action— Affinity5.3 Kd SourceDRUGCENTRAL |
| 5-hydroxytryptamine receptor 2A (Htr2a) | — | 8.7 Ki | DRUGCENTRAL | Target5-hydroxytryptamine receptor 2A (Htr2a) Action— Affinity8.7 Ki SourceDRUGCENTRAL |
| 5-hydroxytryptamine receptor 2C (Htr2c) | — | 8.26 Ki | DRUGCENTRAL | Target5-hydroxytryptamine receptor 2C (Htr2c) Action— Affinity8.26 Ki SourceDRUGCENTRAL |
| 5-hydroxytryptamine receptor 3A (HTR3A) | — | 5.54 Ki | DRUGCENTRAL | Target5-hydroxytryptamine receptor 3A (HTR3A) Action— Affinity5.54 Ki SourceDRUGCENTRAL |
| 5-hydroxytryptamine receptor 7 (HTR7) | — | 6.58 Ki | DRUGCENTRAL | Target5-hydroxytryptamine receptor 7 (HTR7) Action— Affinity6.58 Ki SourceDRUGCENTRAL |
| Adrenergic receptor alpha-1 (Adra1b) | — | 6.22 Ki | DRUGCENTRAL | TargetAdrenergic receptor alpha-1 (Adra1b) Action— Affinity6.22 Ki SourceDRUGCENTRAL |
| Alpha-1A adrenergic receptor (ADRA1A) | — | 5.5 IC50 | DRUGCENTRAL | TargetAlpha-1A adrenergic receptor (ADRA1A) Action— Affinity5.5 IC50 SourceDRUGCENTRAL |
| D(1A) dopamine receptor (DRD1) | — | 5.38 Ki | DRUGCENTRAL | TargetD(1A) dopamine receptor (DRD1) Action— Affinity5.38 Ki SourceDRUGCENTRAL |
| D(2) dopamine receptor (DRD2) | — | 5.263 Ki | DRUGCENTRAL | TargetD(2) dopamine receptor (DRD2) Action— Affinity5.263 Ki SourceDRUGCENTRAL |
| D(3) dopamine receptor (DRD3) | — | 5.24 Ki | DRUGCENTRAL | TargetD(3) dopamine receptor (DRD3) Action— Affinity5.24 Ki SourceDRUGCENTRAL |
| Histamine H1 receptor (HRH1) | — | 8.796 Ki | DRUGCENTRAL | TargetHistamine H1 receptor (HRH1) Action— Affinity8.796 Ki SourceDRUGCENTRAL |
| Muscarinic acetylcholine receptor M1 (CHRM1) | — | — | DRUGCENTRAL | TargetMuscarinic acetylcholine receptor M1 (CHRM1) Action— Affinity— SourceDRUGCENTRAL |
| Muscarinic acetylcholine receptor M2 (CHRM2) | — | — | DRUGCENTRAL | TargetMuscarinic acetylcholine receptor M2 (CHRM2) Action— Affinity— SourceDRUGCENTRAL |
| Sodium-dependent noradrenaline transporter (SLC6A2) | — | 5.337 Ki | DRUGCENTRAL | TargetSodium-dependent noradrenaline transporter (SLC6A2) Action— Affinity5.337 Ki SourceDRUGCENTRAL |
| Transporter (Slc6a2) | — | 5.79 Ki | DRUGCENTRAL | TargetTransporter (Slc6a2) Action— Affinity5.79 Ki SourceDRUGCENTRAL |
External links
PubChem 4205 ↗CAS 61337-67-5 ↗CAS 85650-52-8 ↗KEGG C07570 ↗ChEBI CHEBI:6950 ↗ChEMBL CHEMBL654 ↗KEGG D00563 ↗DrugBank DB00370 ↗ChemSpider ↗ChEBI/ChEMBL ↗Guide to Pharmacology ↗NIH ↗NIH ↗NIH ↗DrugBank ↗ChEBI/ChEMBL ↗CAS 1216678-68-0 ↗CAS 159355-60-9 ↗CAS 207516-99-2 ↗CAS 61337-87-9 ↗CAS 61364-37-2 ↗PsychonautWiki ↗Erowid ↗Experience reports (PiHKAL) ↗Experience reports (TiHKAL) ↗
Source: DrugCentral — Mirtazapine ↗
Fact-sheets from PsychonautWiki. Harm-reduction reference only — not medical advice.