Modafinil
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4 sources
How the databases line up — = agree, ≈ partial, ≠ differ. In lists, shared items appear in every source and unique ones in only one (matched case-insensitively).
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| PsychonautWiki | TripSit | Pharmacology | DrugCentral | ||
|---|---|---|---|---|---|
| Classification | |||||
| Class / category | — | — | ≈ | ||
| Also known as | ModafinilAlertecModavigilModiodalProvigilModalert | provigil | — | — | ≈ |
| Safety | |||||
| Addiction potential | not addictive with a low potential for abuse | — | — | — | |
| Toxicity | The median lethal dose at which 50% of participants die (LD50) from modafinil for human beings has never been reached | — | — | — | |
| Dangerous interactions | — | — | — | ||
| Unsafe interactions | — | — | — | ||
| Dose · Oral | |||||
| Threshold | 25 mg | — | — | — | |
| Light | 50–100 mg | — | — | — | |
| Common | 100–200 mg | 100–300 mg | — | — | ≠ |
| Strong | 200–300 mg | — | — | — | |
| Heavy | 300 mg+ | — | — | — | |
| Duration | |||||
| Onset | 20–60 minutes | 30–45 minutes | — | — | ≠ |
| Total | 5–10 hours | 12–16 hours | — | — | ≠ |
| After-effects | 2–6 hours | 1–16 hours | — | — | ≠ |
| Pharmacology | |||||
| Receptor activity | — | — | Sodium-dependent dopamine transporterUnchecked | SLC6A3ADRA1BCYP1A2CYP2C19DRD2NET | ≠ |
| Half-life | — | — | 23-215 hours Elimination: Effectively, about 15 hours after multiple dosing; the elimination half life of the levo-isomer is about three times that of the dextro-isomer. ... Modafinil was rapidly absorbed after oral dosing and slowly cleared (half life approximately 11-14 hr) from the body. | — | |
| Protein binding | — | — | 60% | — | |
Dose at a glance
Each database's primary-route ladder on one shared scale — see where ranges line up or shift.
PsychonautWiki oral
TripSit Oral
0375 mg
LightCommonStrongHeavy
Duration at a glance
Total duration on one shared scale.
PsychonautWiki
TripSit
TripSit summary
A wakefulness promoting, long acting stimulant which is typically only used functionally, because there is no real euphoric component to its effects. Also prescribed for daytime sleeping disorders.
Fact-sheets from PsychonautWiki. Harm-reduction reference only — not medical advice.