Modafinil
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4 sources
🧬 Receptor activity
| Target | Action | Affinity | Source | |
|---|---|---|---|---|
| Sodium-dependent dopamine transporter (SLC6A3) | Inhibitor | 5.837 Ki | DRUGCENTRAL | TargetSodium-dependent dopamine transporter (SLC6A3) ActionInhibitor Affinity5.837 Ki SourceDRUGCENTRAL |
| Alpha-1B adrenergic receptor (ADRA1B) | — | — | DRUGCENTRAL | TargetAlpha-1B adrenergic receptor (ADRA1B) Action— Affinity— SourceDRUGCENTRAL |
| Cytochrome P450 1A2 (CYP1A2) | — | 4.396 Ki | DRUGCENTRAL | TargetCytochrome P450 1A2 (CYP1A2) Action— Affinity4.396 Ki SourceDRUGCENTRAL |
| Cytochrome P450 2C19 (CYP2C19) | — | — | DRUGCENTRAL | TargetCytochrome P450 2C19 (CYP2C19) Action— Affinity— SourceDRUGCENTRAL |
| D(2) dopamine receptor (DRD2) | — | 6.62 EC50 | DRUGCENTRAL | TargetD(2) dopamine receptor (DRD2) Action— Affinity6.62 EC50 SourceDRUGCENTRAL |
| Sodium-dependent dopamine transporter (Slc6a3) | — | 5.6 Ki | DRUGCENTRAL | TargetSodium-dependent dopamine transporter (Slc6a3) Action— Affinity5.6 Ki SourceDRUGCENTRAL |
| Transporter (NET) | — | 4.19 IC50 | DRUGCENTRAL | TargetTransporter (NET) Action— Affinity4.19 IC50 SourceDRUGCENTRAL |
External links
PubChem 4236 ↗CAS 68693-11-8 ↗ChEBI CHEBI:77585 ↗ChEMBL CHEMBL1373 ↗KEGG D01832 ↗DrugBank DB00745 ↗NIH ↗NIH ↗NIH ↗NIH ↗ChemSpider ↗ChEBI/ChEMBL ↗Guide to Pharmacology ↗NIH ↗NIH ↗NIH ↗NIH ↗DrugBank ↗ChEBI/ChEMBL ↗CAS 112111-43-0 ↗CAS 112111-47-4 ↗CAS 112111-49-6 ↗CAS 1219804-30-4 ↗CAS 68692-83-1 ↗PsychonautWiki ↗Erowid ↗Experience reports (PiHKAL) ↗Experience reports (TiHKAL) ↗
Source: DrugCentral — Modafinil ↗
Fact-sheets from PsychonautWiki. Harm-reduction reference only — not medical advice.