Morphine
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5 sources
Also known as Morphine, MS-Contin, Oramorph, Zomorph, Sevredol, Duramorph
Fatal overdose may occur when opiates are combined with other depressants such as benzodiazepines, barbiturates, gabapentinoids, thienodiazepines, alcohol or other GABAergic substances.[1] It is strongly discouraged to combine these substances, particularly in common to heavy doses.
Cross-tolerance
opioids
Intravenous
Route dataPsychonautWiki
| Threshold | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| 3.33 mg | 3.33–5 mg | 5–7.5 mg | 7.5–10 mg | 10 mg+ |
012.5 mg
LightCommonStrongHeavy
| Onset | 0–30 seconds |
|---|---|
| Come-up | 2–5 minutes |
| Peak | 1.5–2.5 hours |
| Offset | 60–90 minutes |
| Total | 4–5 hours |
OnsetCome-upPeakOffset
Oral
Route dataPsychonautWiki
| Threshold | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| 10 mg | 10–15 mg | 15–20 mg | 20–30 mg | 30 mg+ |
037.5 mg
LightCommonStrongHeavy
| Onset | 10–30 minutes |
|---|---|
| Come-up | 20–40 minutes |
| Peak | 2–3 hours |
| Offset | 1–2 hours |
| Total | 4–6 hours |
OnsetCome-upPeakOffset
Bioavailability: 35–40 %
Dangerous interactions
Caution / uncertain
Plan when to take Morphine — see where onset, peak and comedown land on the clock
Plan a dose of Morphine
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Source: PsychonautWiki — Morphine ↗
Fact-sheets from PsychonautWiki. Harm-reduction reference only — not medical advice.