4 sources
Also known as Naloxone, Narcan, Evzio
Experts now advise that anyone using street drugs—and those around them—should carry naloxone, as opioids are increasingly found contaminating the drug supply. Having naloxone on hand can save lives by reversing overdoses, even if opioids were not intentionally consumed.[1] Summary sheet: Naloxone
Addiction potential
not habit-forming
Insufflated
Route dataPsychonautWiki
| Threshold | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| — | — | 1–4 mg | — | —+ |
04 mg
LightCommonStrongHeavy
| Onset | 0–10 minutes |
|---|---|
| Total | 30–60 minutes |
OnsetCome-upPeakOffset
Intramuscular
Route dataPsychonautWiki
| Threshold | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| — | — | 0.4–2 mg | — | —+ |
02 mg
LightCommonStrongHeavy
| Onset | 0.25–2 minutes |
|---|---|
| Total | 30–60 minutes |
OnsetCome-upPeakOffset
Intravenous
Route dataPsychonautWiki
| Threshold | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| — | — | 0.4–2 mg | — | —+ |
02 mg
LightCommonStrongHeavy
| Onset | 0.25–2 minutes |
|---|---|
| Total | 30–60 minutes |
OnsetCome-upPeakOffset
Oral
Route dataPsychonautWiki
| Threshold | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| 4 mg | 4–8 mg | 8–16 mg | 16–28 mg | 28 mg+ |
035 mg
LightCommonStrongHeavy
| Onset | 5–15 minutes |
|---|---|
| Come-up | 20–40 minutes |
| Peak | 1–2 hours |
| Offset | 30–60 minutes |
| Total | 1–2 hours |
| After-effects | 1–12 hours |
OnsetCome-upPeakOffset
Plan when to take Naloxone — see where onset, peak and comedown land on the clock
Plan a dose of Naloxone
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Source: PsychonautWiki — Naloxone ↗
Fact-sheets from PsychonautWiki. Harm-reduction reference only — not medical advice.